metaEvidence COVID-19 - living meta-analysis

button bars forest bayes pooled summary circles

Treament	Trials
Treament	Trials	Statistically conclusive or suggested result	Inconclusive results	Uncertain results	Safety results
study description meta-analysis results	0	-	-	-	-
study description meta-analysis results	0	-	-	-	-
study description meta-analysis results	3	statistically conclusive 38 % increase in clinical improvement suggested 57 % increase in clinical improvement (14-day) suggested 81 % increase in clinical improvement (28-day) suggested 47 % decrease in serious adverse events	inconclusive results for: death D28; deaths; deaths (time to event analysis only); clinical improvement (7-day); clinical improvement (time to event analysis only); mechanical ventilation; recovery; adverse events	-	-
study description meta-analysis results	1 / 2	none	inconclusive results for: death D28; death or transfer to ICU; deaths; mechanical ventilation; viral clearance by day 7; ICU admission	statistically conclusive 48 % decrease in clinical deterioration but the degree if certainty is unassessable	-
study description meta-analysis results	0 / 2	none	inconclusive results for: deaths; hospital discharge; ICU admission	-	-
study description meta-analysis results	0	-	-	-	-
study description meta-analysis results	0 / 1	none	inconclusive results for: deaths	-	-
study description meta-analysis results	1	none	-	suggested 39 % decrease in death D28 but the degree if certainty is unassessable suggested 39 % decrease in deaths but the degree if certainty is unassessable suggested 34 % decrease in death or ventilation but the degree if certainty is unassessable suggested 48 % increase in hospital discharge but the degree if certainty is unassessable	-
study description meta-analysis results	4	suggested 2.7-fold increase in viral clearance by day 7	inconclusive results for: death D28; deaths; clinical improvement; clinical improvement (14-day); hospitalization; viral clearance ; viral clearance (time to event analysis only); viral clearance by day 14; serious adverse events; adverse events	suggested 91 % increase in clinical improvement (7-day) but the degree if certainty is unassessable	-
study description meta-analysis results	0 / 1	none	inconclusive results for: deaths; deaths (time to event analysis only)	-	-
study description meta-analysis results	0	-	-	-	-
study description meta-analysis results	1	none	inconclusive results for: deaths; death or ventilation; Major bleeding	statistically conclusive 27 % increase in clinical improvement (28-day) but the degree if certainty is unassessable	-
study description meta-analysis results	0	-	-	-	-

Statistically conclusive: statistically significant with a strict control of overall risk of type 1 error (statistically demonstrated), does not take into account the risk of bias; suggested: nominally statistically significant but without a strict control of overall risk of type 1 error; inconclusive: not nominally statistically significant

Living meta-analysis and evidence synthesis of therapies for COVID19